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Trials designed to inform clinical practice in the real world are known as pragmatic trials. They are typically described as a focus on the practical aspects of designing a study, including the recruitment process and consent, adhering and the use routinely available equipment.

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A pragmatic study that involves various investigators and participants from different geographical areas is the Home Blood Pressure Management study (HBPM). This kind of heterogeneity is required for pragmatic trials to be valid and also reduces bias in the results. However excessive heterogeneity could cause problems with the design of the trial.

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The purpose of pragmatic trials is to replicate real-life situations and achieve maximum validity externally. They are usually commissioned by practitioners and policy makers to aid in their decision-making. They can also be used to assess the cause-effect relationship of an intervention and its results. However, 프라그마틱 슈가러쉬 (visit the website) they shouldn't be used to substitute for explanatory studies.

The idea of pragmatism is controversial and there are doubts about whether pragmatic trials can replace tests for explanations or if they should be an addition to them. Schwartz and Lellouch1 suggested the distinction between explanation studies, which support the physiological hypothesis or clinical hypothesis, and pragmatic trials, that inform policy and practice decision-making. They also suggested an approach to pragmatic trials, which they called PRECIS.2 This tool sought to define the elements of a practical trial which includes the recruitment process, the design and delivery of the intervention, as well as the follow-up.

The number of pragmatic trials is growing. A recent Medline search using the terms pragmatic and 프라그마틱 정품 사이트 - homesite - naturalistic, restricted to randomized controlled trials (RCTs) produced 34 articles, shown in red in Figure 2. This suggests that the health sciences community has become more aware of the importance of pragmatism. However, it is important to remember that the majority of these trials were conducted in primary care settings.